Author

B. Spronck

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 3 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. B. Ramachandra· 3 shared A. Giudici· 2 shared G. Tellides· 2 shared M. Wang· 2 shared S.-I. Murtada· 2 shared A. Rojas· 1 shared A. W. Caulk· 1 shared B. Jiang· 1 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersBioengineering

A. B. Ramachandra

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4 papers

Recent·Most cited

Instability in computational models of vascular smooth muscle cell contraction

A. Giudici, J. M. Szafron, A. B. Ramachandra, B. Spronck

This paper identifies unstable behaviors in active stress models of vascular smooth muscle cell contraction using limited and extensive experimental data.

bioRxiv · Oct 16, 2023Biophysics

Evaluating flash freezing for preservation of rat abdominal aorta for delayed biomechanical characterization

K. W. F. van der Laan, K. Reesink, S. Lambrichts, N. J. J. E. Bitsch, L. van der Taelen, S. Foulquier, T. Delhaas, B. Spronck, A. Giudici

This study evaluates flash freezing as a method for preserving rat abdominal aortas for delayed biomechanical testing, finding it suitable for passive biomechanics with some structural changes.

bioRxiv · Oct 16, 2023 · PreprintBioengineering

Smooth Muscle Cell Death Drives an Osteochondrogenic Phenotype and Severe Proximal Vascular Disease in Progeria

S.-I. Murtada, Y. Kawamura, C. Cavinato, M. Wang, A. B. Ramachandra, B. Spronck, G. Tellides, J. Humphrey

This study links smooth muscle cell death to osteochondrogenic changes and vascular disease in progeria, identifying a sequence of pathological events leading to cardiovascular complications.

bioRxiv · Jan 10, 2023 · PreprintBioengineering

Genetic Background Dictates Aortic Fibrosis in Hypertensive Mice

B. Spronck, M. Latorre, S. Mehta, A. W. Caulk, A. B. Ramachandra, S.-I. Murtada, A. Rojas, C.-S. He, B. Jiang, M. Wang, M. R. Bersi, G. Tellides, J. D. Humphrey

This study shows that genetic background strain influences aortic fibrosis in hypertensive mice, with C57BL/6J mice showing more maladaptive remodeling than 129SvEv mice.

bioRxiv · May 5, 2020Bioengineering