Rho/ROCK activity tunes cell compartment segregation and differentiation in nephron-forming niches
J. M. Viola, J. Liu, A. Huang, S. H. Grindel, L. S. Prahl, A. J. Hughes
This study shows that Rho/ROCK inhibition enhances mixing between nephron progenitor and stromal cells, increasing nephrogenesis in kidney organoids.
bioRxiv · Nov 8, 2023 · PreprintBioengineering