Author

J. M. Wang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

A. J. Dafferner· 1 shared A. Kolovou· 1 shared B. A. Teply· 1 shared C. Bussi· 1 shared C. Morrissey· 1 shared D. Costanzo-Garvey· 1 shared D. S. Arroyo· 1 shared D. W. McVicar· 1 shared

Activity by Year

2017-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

A. J. Dafferner

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2 papers

Recent·Most cited

Androgen-mediated TGFβ expression suppresses anti-tumor neutrophil response in bone metastatic prostate cancer

M. Alsamraae, D. Costanzo-Garvey, B. A. Teply, S. Boyle, G. Sommerville, Z. Herbert, C. Morrissey, A. J. Dafferner, M. Y. Abdalla, R. W. Fallet, T. Kielian, H. Jensen-Smith, E. I. deOliveira, K. Chen, I. A. Bettencourt, , L. M. Cook

This study identifies androgen-mediated TGFβ expression as a mechanism suppressing anti-tumor neutrophil response in bone metastatic prostate cancer and shows that combining ADT with TGFβ receptor inhibition restores neutrophil cytotoxicity.

bioRxiv · Dec 30, 2022 · PreprintCancer Biology

Alpha-synuclein fibrils induce autophagy in microglial cells as a consequence of lysosomal damage.

C. Bussi, J. M. Peralta Ramos, D. S. Arroyo, J. I. Gallea, P. Ronchi, A. Kolovou, J. M. Wang, O. Florey, M. S. Celej, Y. Schwab, N. T. Ktistakis, P. Iribarren

This study shows that alpha-synuclein fibrils cause lysosomal damage and autophagy in microglial cells, leading to mitochondrial dysfunction and cell death.

bioRxiv · Jul 27, 2017Cell Biology