Author
J. McClure
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
Biology Disciplines
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2019-2023 · peak 4/yrCo-Author Collaboration Network
10 top collaborators · 28 mutual co-author links6 papers
Recent·Most cited
The intraosseous expansion of primary chondrosarcoma is achieved by osteoclasts expressing GnTase V (MGAT5) activity to drive neoangiogenesis.
The paper investigates how primary chondrosarcoma expands by osteoclasts expressing GnTase V (MGAT5) to drive neoangiogenesis and bone resorption.
bioRxiv · Feb 13, 2023 · PreprintPathology
Chondro/osteoclasts and mast cells are co-villains in the joint destruction of rheumatoid arthritis
The paper investigates the role of chondro/osteoclasts and mast cells in joint destruction in rheumatoid arthritis, showing their microanatomical relationship and angiogenic function.
bioRxiv · Jan 4, 2023 · PreprintPathology
Study of the glycome of synovial mast cells in normal tissues, osteoarthritis and rheumatoid arthritis reveals MGAT5 activity in these and endochondral cells.
The paper examines the glycome of synovial mast cells in normal and diseased tissues, finding increased mast cell numbers in arthritis and linking MGAT5 activity to mast cell and endothelial cell interactions.
bioRxiv · May 19, 2022 · PreprintPathology
Transforming growth factor-beta signaling via ALK1 and ALK5 regulates distinct functional pathways in vein graft intimal hyperplasia
A. Bradshaw, E. Low, J. T. Schwartze, A. Kurkiewicz, M. Pek, D. Kelly, A. Shaw, M. Thorikay, J. McClure, M. McBride, S. Arias-Rivas, S. E. Francis, N. Morrell, C. Delles, P. Herzyk, , A. H. Baker
This study shows TGF{beta} signals through ALK1 and ALK5 in vein graft SMCs, with ALK5 promoting contractility and ALK1 driving migration, suggesting balancing these pathways could prevent graft failure.
bioRxiv · Nov 29, 2019 · PreprintCell Biology