A glycogenin homolog controls Toxoplasma gondii growth via glycosylation of an E3 ubiquitin ligase
M. Mandalasi, H. W. Kim, D. Thieker, M. O. Sheikh, E. Gas-Pascual, K. Rahman, P. Zhao, N. G. Daniel, H. van der Wel, T. H. Ichikawa, J. N. Glushka, L. Wells, R. J. Woods, Z. A. Wood, C. M. West
This study identifies Gat1, a glycogenin homolog, as essential for adding the terminal sugar to Skp1 in Toxoplasma gondii, which is critical for parasite growth.
bioRxiv · Feb 2, 2020 · PreprintMicrobiology