Author

H. W. Kim

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4 Biochemistry· 2 Evolutionary Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Organism:human· 4 Research Focus:chromatin & epigenetic regulation· 3 Research Focus:host-pathogen & immune response· 3 Assay:proteomics· 3 Assay:protein structure· 2 Approach:statistical model· 2 Organism:Arabidopsis· 1

Frequent Co-Authors

C. M. West· 2 shared D. Basu· 2 shared E. A. White· 2 shared H. van der Wel· 2 shared P. Castagnino· 2 shared Z. A. Wood· 2 shared A. Eletsky· 1 shared A. Guha· 1 shared

Activity by Year

2017-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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2 shared papersMicrobiology

C. M. West

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Hepatocyte-specific disruption of soluble epoxide hydrolase attenuates abdominal aortic aneurysm formation: novel role of the liver in aneurysm pathogenesis

D. Kim, T. Horimatsu, M. Ogbi, B. Goo, H. Shi, P. Veerapaneni, R. Chouhaita, M. Moses, R. Prasad, T. W. Benson, R. Harb, G. Aboud, H. Sellers, S. Haigh, D. J. R. Fulton, , H. W. Kim

This study shows that disrupting soluble epoxide hydrolase (sEH) in the liver prevents abdominal aortic aneurysm (AAA) formation by reducing inflammatory factors like C3 and SAA.

bioRxiv · Jul 10, 2023 · PreprintPharmacology & Toxicology

Systematic analysis of IL-1 cytokine signaling suppression by high-risk HPV oncoproteins

P. Castagnino, H. W. Kim, L. K. M. Lam, D. Basu, E. A. White

This study shows that HPV16 E6 and E7 oncoproteins suppress IL-1β signaling in both early and late stages of HPV-induced carcinogenesis by upregulating suppressors like SIGIRR.

bioRxiv · Aug 25, 2022Microbiology

YAP1 Activation by Human Papillomavirus E7 Promotes Basal Cell Identity in Squamous Epithelia

J. Hatterschide, P. Castagnino, H. W. Kim, S. M. Sperry, K. T. Montone, D. Basu, E. A. White

This study shows that HPV E7 activates YAP1, promoting basal cell identity and contributing to HPV persistence and carcinogenesis.

bioRxiv · Nov 10, 2021Microbiology

A glycogenin homolog controls Toxoplasma gondii growth via glycosylation of an E3 ubiquitin ligase

M. Mandalasi, H. W. Kim, D. Thieker, M. O. Sheikh, E. Gas-Pascual, K. Rahman, P. Zhao, N. G. Daniel, H. van der Wel, T. H. Ichikawa, J. N. Glushka, L. Wells, R. J. Woods, Z. A. Wood, C. M. West

This study identifies Gat1, a glycogenin homolog, as essential for adding the terminal sugar to Skp1 in Toxoplasma gondii, which is critical for parasite growth.

bioRxiv · Feb 2, 2020 · PreprintMicrobiology

Skp1 Dimerization Conceals its F-box Protein Binding Site

H. W. Kim, A. Eletsky, K. J. Gonzalez, H. van der Wel, E.-M. Strauch, J. H. Prestegard, C. M. West

This paper investigates how Skp1 dimerization hides its F-box protein binding site, showing that a mutation disrupts dimerization and allows Skp1 to bind F-box proteins.

bioRxiv · Jan 26, 2020Biochemistry

A novel redox-active switch in Fructosamine-3-kinases expands the regulatory repertoire of the protein kinase superfamily

S. Shrestha, S. Katiyar, C. E. Sanz-Rodriguez, N. R. Kemppinen, H. W. Kim, R. Kadirvelraj, C. Panagos, N. Keyhaninejad, M. Colonna, P. Chopra, D. P. Byrne, G. J. Boons, E. V. Knaap, P. Eyers, A. S. Edison, , N. Kannan

This study identifies redox-sensitive cysteines in Fructosamine-3-kinases (FN3Ks) that regulate their activity and dimerization through disulfide bonds, revealing a novel redox regulatory mechanism in the protein kinase superfamily.

bioRxiv · Jan 13, 2020Biochemistry

Inhibitory effects of β-caryophyllene on Helicobacter pylori infection in vitro and in vivo

H. J. Woo, J. Y. Yang, M. H. Lee, H. W. Kim, H. J. Kwon, M. Park, S.-k. Kim, S.-Y. Park, S.-H. Kim, J.-B. Kim

This study demonstrates that β-caryophyllene inhibits H. pylori growth and infection through downregulation of virulence factors and bacterial replication machinery, with therapeutic effects confirmed in vivo.

bioRxiv · Nov 18, 2019Microbiology

Population genomic analysis reveals contrasting demographic changes of two closely related dolphin species in the last glacial

N. Vijay, C. Park, J. Oh, S. Jin, E. Kern, H. W. Kim, J. Zhang, J.-K. Park

The paper analyzes population genomic data of two dolphin species to show contrasting demographic changes during the last glacial period.

bioRxiv · Nov 28, 2017Evolutionary Biology