Author

J. P. Henderson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 5 Biochemistry· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:host-pathogen & immune response· 6 Organism:E. coli· 3 Organism:human· 3 Approach:statistical model· 3 Assay:metabolomics· 2 Assay:proteomics· 2 Research Focus:clustering· 1

Frequent Co-Authors

J. I. Robinson· 3 shared G. Dantas· 2 shared G. L. Katumba· 2 shared J. B. Case· 2 shared M. S. Diamond· 2 shared R. E. Chen· 2 shared W. H. McCoy· 2 shared Z. Zou· 2 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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3 shared papersMicrobiology

J. I. Robinson

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Uropathogenic Escherichia coli wield enterobactin-derived catabolites as siderophores

Z. Zou, J. I. Robinson, L. K. Steinberg, J. P. Henderson

This study identifies enterobactin and its catabolites as functional siderophores in UPEC, showing incomplete hydrolysis allows for multiple iron acquisitions per molecule.

bioRxiv · Jul 25, 2023 · PreprintBiochemistry

Yersiniabactin is a quorum sensing autoinducer and siderophore in uropathogenic Escherichia coli

J. R. Heffernan, G. L. Katumba, W. H. McCoy, J. P. Henderson

This study shows that yersiniabactin in uropathogenic E. coli functions as both a siderophore and a quorum-sensing autoinducer, with non-redundant roles in iron acquisition and bacterial density-dependent regulation.

bioRxiv · Feb 9, 2023 · PreprintMicrobiology

Multi-omics investigation of Clostridioides difficile-colonized patients reveals protective commensal carbohydrate metabolism

S. R. S. Fishbein, J. I. Robinson, T. Hink, K. A. Reske, E. P. Newcomer, C.-A. D. Burnham, J. P. Henderson, E. R. Dubberke, G. Dantas

This study identifies carbohydrate metabolism by commensal Clostridia as protective against C. difficile infection in asymptomatic carriers.

bioRxiv · Aug 24, 2021Microbiology

Pathogenic potential in catheter associated Escherichia coli is associated with separable biofilm and virulence gene determinants

Z. Zou, R. F. Potter, W. H. McCoy, G. L. Katumba, P. J. Mucha, G. Dantas, J. P. Henderson

This study identifies distinct genetic determinants for biofilm formation and virulence in E. coli associated with catheter-related infections.

bioRxiv · Jul 16, 2021 · PreprintMicrobiology

Association between neutralizing antibodies to SARS-CoV-2 and commercial serological assays

M. S. Tang, J. B. Case, C. E. Franks, R. E. Chen, N. W. Anderson, J. P. Henderson, M. S. Diamond, A. M. Gronowski, C. W. Farnsworth

This study evaluates the association between SARS-CoV-2 neutralizing antibodies and results from three commercial serological assays, finding moderate correlations and varying agreement rates.

bioRxiv · Jul 1, 2020Immunology

Neutralizing antibody and soluble ACE2 inhibition of a replication-competent VSV-SARS-CoV-2 and a clinical isolate of SARS-CoV-2.

J. B. Case, P. W. Rothlauf, R. E. Chen, Z. Liu, H. Zhao, A. S. Kim, L.-M. Bloyet, Q. Zeng, S. Tahan, L. Droit, M. X. G. Ilagan, M. A. Tartell, G. K. Amarasinghe, J. P. Henderson, S. Miersch, , S. P. J. Whelan

This study develops two neutralization assays for SARS-CoV-2 using VSV and a clinical isolate, showing high concordance between monoclonal, polyclonal antibodies, and ACE2-Fc in neutralizing activity.

bioRxiv · May 18, 2020Microbiology

The commercial antimicrobial triclosan induces high levels of antibiotic tolerance in vitro and reduces antibiotic efficacy up to 100-fold in vivo

C. S. Westfall, A. L. Flores-Mireles, J. I. Robinson, A. J. L. Lynch, S. Hultgren, J. P. Henderson, P. A. Levin

This paper shows triclosan increases antibiotic tolerance in bacteria and reduces antibiotic efficacy in mice.

bioRxiv · Dec 5, 2018 · PreprintMicrobiology