Author

J. P. Nguyen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:drug response / drug discovery· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1

Frequent Co-Authors

J. A. Hirota· 2 shared A. Chandiramohan· 1 shared C. A. Jimenez Hoyos· 1 shared C. A. Smith· 1 shared E. R. Hostetter· 1 shared G. Xu· 1 shared I. Poon· 1 shared J. Nite· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersBioengineering

J. A. Hirota

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Author profile →

3 papers

Recent·Most cited

Prediction of fluorophore brightness in designed mini fluorescence activating proteins

E. R. Hostetter, J. R. Keyes, I. Poon, J. P. Nguyen, J. Nite, Molecular Modeling and Design Class, C. A. Jimenez Hoyos, C. A. Smith

The paper uses quantum mechanics and molecular dynamics simulations to predict fluorophore brightness in designed mini fluorescence activating proteins by analyzing molecular flexibility.

bioRxiv · Jul 21, 2021Biophysics

PHAIR, A biosensor for pH measurement in air-liquid interface of human airway epithelial cells

M. Dabaghi, N. Saraei, G. Xu, A. Chandiramohan, J. Yeung, J. P. Nguyen, M. Vukmirovic, P. R. Selvaganapathy, J. A. Hirota

The paper introduces PHAIR, a pH sensor for measuring pH in human airway epithelial cells, showing it does not affect cell viability or cytokine responses.

bioRxiv · Nov 9, 2020 · PreprintBioengineering

Modulation of cAMP metabolism for CFTR potentiation in human airway epithelial cells

J. P. Nguyen, M. Bianca, R. D. Huff, N. Tiessen, M. D. Inman, J. A. Hirota

This study tests cAMP modulation via ABCC4 and PDE-4 inhibition as an add-on therapy to VX-770 to increase CFTR activity in human airway epithelial cells.

bioRxiv · Sep 11, 2020Cell Biology