Author

J. Yeung

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4 Immunology· 4 Microbiology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Organism:human· 7 Research Focus:cell type annotation· 6 Approach:experimental assay· 6 Research Focus:host-pathogen & immune response· 4 Organism:mouse· 4 Assay:scRNA-seq· 4 Approach:deep learning· 3 Research Focus:differential expression· 3

Frequent Co-Authors

B. Zhu· 3 shared G. P. Nolan· 3 shared H. Chen· 3 shared S. Jiang· 3 shared S. Keshavjee· 3 shared S. Moshkelgosha· 3 shared T. Martinu· 3 shared Y. Bai· 3 shared

Activity by Year

2020-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersCancer Biology

B. Zhu

Mutual co-authors in cluster

Author profile →

11 papers

Recent·Most cited

Epstein-Barr Virus Orchestrates Spatial Reorganization and Immunomodulation within the Classic Hodgkin Lymphoma Tumor Microenvironment

Y. Y. Yeo, H. Qiu, Y. Bai, B. Zhu, Y. Chang, J. Yeung, H. A. Michel, K. T. Wright, M. Shaban, S. Sadigh, D. Nkosi, V. Shanmugam, S. P. T. Yiu, P. Cramer, P. Rock, , S. Jiang

This study uses spatial multi-omics to compare EBV-positive and EBV-negative cHL, identifying distinct TME features and immunological signatures linked to EBV.

bioRxiv · Mar 5, 2024Cancer Biology

A Spatial Multi-Modal Dissection of Host-Microbiome Interactions within the Colitis Tissue Microenvironment

B. Zhu, Y. Bai, Y. Y. Yeo, X. Lu, X. Rovira-Clave, H. Chen, J. Yeung, G. K. Gerber, M. Angelo, A. K. Shalek, G. P. Nolan, S. Jiang

This study introduces MicroCart, a framework for spatial multi-omics analysis of host-microbiome interactions in colitis, revealing tissue-level immune responses and microbial shifts.

bioRxiv · Mar 4, 2024 · PreprintImmunology

Emergence of a senescent and inflammatory pulmonary CD4+ T cell population prior to lung allograft failure

S. Moshkelgosha, L. Levy, S. Safavi, S. Karunagaran, G. Wilson, B. Renaud-Picard, G. Madu, R. Ramchandani, J. Oliver, T. Watanabe, K. F. Bei, B. Joe, Q. Li, E. Huszti, M. Cheung, , S. Juvet

The paper identifies CD4+CD57+PD1+ T cells in lung transplant recipients that predict allograft dysfunction and are associated with fibrosis in both human and mouse models.

bioRxiv · Dec 19, 2023Immunology

MAPS: Pathologist-level cell type annotation from tissue images through machine learning

M. Shaban, Y. Bai, H. Qiu, S. Mao, J. Yeung, Y. Y. Yeo, V. Shanmugam, V. Shanmugam, H. Chen, B. Zhu, G. P. Nolan, M. A. Shipp, S. J. Rodig, S. Jiang, F. Mahmood

MAPS provides pathologist-level cell type annotation from spatial proteomics data using machine learning, outperforming existing methods in speed and accuracy.

bioRxiv · Jun 25, 2023 · PreprintCancer Biology

A single-dose of intranasal vaccination with a live-attenuated SARS-CoV-2 vaccine candidate promotes protective mucosal and systemic immunity

A. Adam, B. Kalveram, J. Y.-C. Chen, J. Yeung, L. Rodriguez, A. Singh, P.-Y. Shi, X. Xie, T. Wang

bioRxiv · Apr 17, 2023Microbiology

Intertumoral lineage diversity and immunosuppressive transcriptional programs in well-differentiated gastroenteropancreatic neuroendocrine tumors

S. E. Hoffman, T. W. Dowrey, C. V. Martin, K. Bi, B. M. Titchen, S. Johri, L. DelloStritto, M. Patel, C. Mackichan, S. Inga, J. Chen, G. Grimaldi, S. Napolitano, I. Wakiro, J. Wu, , G. J. Murphy

This study analyzes single-cell transcriptomes of gastroenteropancreatic neuroendocrine tumors to identify lineage diversity and immunosuppressive programs in tumor and immune cells.

bioRxiv · Nov 8, 2022Cancer Biology

Cross-neutralization and viral fitness of SARS-CoV-2 Omicron sublineages

H. Xia, J. Yeung, B. Kalveram, C. J. Bills, J. Y.-C. Chen, C. Kurhade, j. Zou, S. G. Widen, B. R. Mann, R. J. Kondor, T. C. Davis, B. Zhou, D. E. Wentworth, X. Xie, P.-Y. Shi

This study examines the replication and cross-neutralization of SARS-CoV-2 Omicron sublineages in mice and human airway cultures, finding distinct antigenic profiles and bivalent vaccine support.

bioRxiv · Nov 8, 2022Microbiology

Interferon-stimulated and metallothionein-expressing macrophages are associated with acute and chronic allograft dysfunction after lung transplantation

S. Moshkelgosha, A. Duong, G. Wilson, T. Andrews, G. Berra, B. Renaud-Picard, M. Liu, S. Keshavjee, S. MacParland, J. Yeung, T. Martinu, S. C. Juvet

The paper identifies two macrophage subsets in lung transplant recipients associated with acute and chronic allograft dysfunction using single-cell RNA sequencing.

bioRxiv · Jun 14, 2021Immunology

Pro-inflammatory alveolar macrophages associated with allograft dysfunction after lung transplantation

S. Moshkelgosha, , G. W. Wilson, A. Duong, T. S. Andrews, B. Renaud, G. Berra, M. Liu, S. Keshavjee, T. Martinu, S. MacParland, J. Yeung, S. C. Juvet

The paper uses scRNA-seq to analyze BAL cells from lung transplant patients, identifying pro-inflammatory macrophage subsets linked to allograft dysfunction.

bioRxiv · Mar 3, 2021 · PreprintImmunology

Multicellular immune hubs and their organization in MMRd and MMRp colorectal cancer

K. Pelka, M. Hofree, J. Chen, S. Sarkizova, J. D. Pirl, V. Jorgji, A. Bejnood, D. Dionne, W. H. Ge, K. H. Xu, S. X. Chao, D. R. Zollinger, D. J. Lieb, J. W. Reeves, C. A. Fuhrman, , J

The paper identifies immune hubs in colorectal cancer by analyzing transcriptional and spatial patterns in MMRd and MMRp tumors.

bioRxiv · Jan 30, 2021 · PreprintCancer Biology

PHAIR, A biosensor for pH measurement in air-liquid interface of human airway epithelial cells

M. Dabaghi, N. Saraei, G. Xu, A. Chandiramohan, J. Yeung, J. P. Nguyen, M. Vukmirovic, P. R. Selvaganapathy, J. A. Hirota

The paper introduces PHAIR, a pH sensor for measuring pH in human airway epithelial cells, showing it does not affect cell viability or cytokine responses.

bioRxiv · Nov 9, 2020 · PreprintBioengineering