Author

J. P. Saeij

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 2 Microbiology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:host-pathogen & immune response· 5 Organism:human· 5 Approach:experimental assay· 4 Organism:mouse· 4 Assay:metagenomics· 2 Assay:proteomics· 2 Organism:chicken / avian· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

D. Mukhopadhyay· 2 shared L. O. Sangare· 2 shared A. Babaian· 1 shared A. Barragan· 1 shared A. Dieng· 1 shared A. Hiller· 1 shared A. L. ten Hoeve· 1 shared A. Morales· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersImmunology

D. Mukhopadhyay

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Hypermigration of macrophages through the concerted action of GRA effectors on NF-κB/p38 signaling and host chromatin accessibility potentiates Toxoplasma dissemination

A. L. ten Hoeve, M. E. Rodriguez, M. Säflund, V. Michel, L. Magimel, A. Ripoll, T. Yu, M.-A. Hakimi, J. P. Saeij, D. M. Ozata, A. Barragan

This study identifies how Toxoplasma gondii uses GRA effectors to manipulate host signaling and chromatin accessibility, promoting macrophage migration and parasite dissemination.

bioRxiv · Feb 6, 2024 · PreprintMicrobiology

A Parasite Odyssey: An RNA virus concealed in Toxoplasma gondii

P. Gupta, A. Hiller, J. Chowdhury, D. Lim, D. Y. Lim, J. P. Saeij, A. Babaian, F. Rodriguez, L. Pereira, A. Morales

The paper identifies a novel narnavirus, Apocryptovirus odysseus, potentially infecting Toxoplasma gondii, and suggests it may act as a pro-inflammatory factor in host cells.

bioRxiv · Sep 17, 2023 · PreprintMicrobiology

Toxoplasma Membrane Inositol Phospholipid Binding Protein TgREMIND Is Essential for Secretory Organelle Function and Host Infection

R. Houngue, L. O. Sangare, T. D. Alayi, A. Dieng, T. Bitard-Feildel, C. Boulogne, C. Slomianny, C. M. Atindehou, L. A. Fanou, Y. Hathout, J. P. Saeij, I. Callebaut, S. Tomavo

bioRxiv · Mar 19, 2023 · PreprintCell Biology

Toxoplasma GRA15 limits parasite growth in IFNγ-activated fibroblasts through TRAF ubiquitin ligases

D. Mukhopadhyay, L. O. Sangare, L. Braun, M. A. Hakimi, J. P. Saeij

The paper identifies GRA15 as a Toxoplasma effector that promotes vacuole destruction in IFNγ-activated fibroblasts by recruiting TRAF ubiquitin ligases.

bioRxiv · Feb 24, 2020Immunology

Toxoplasma GRA15 and GRA24 are important activators of the host innate immune response in the absence of TLR11

D. Mukhopadhyay, D. Arranz-Solis, J. P. Saeij

This study identifies GRA15 and GRA24 as key activators of the innate immune response in Tlr11-/- mice and human cells lacking TLR11/TLR12, showing their role in IL12, IL18, and IL1β secretion and subsequent IFNγ production.

bioRxiv · Feb 14, 2020Immunology