Author

D. M. Ozata

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

A. Kucukural· 2 shared H. Mou· 2 shared S. Beyaz· 2 shared A. Arif· 1 shared A. Barragan· 1 shared A. Erdemir· 1 shared A. Garipcan· 1 shared A. L. ten Hoeve· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersCancer Biology

A. Kucukural

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Hypermigration of macrophages through the concerted action of GRA effectors on NF-κB/p38 signaling and host chromatin accessibility potentiates Toxoplasma dissemination

A. L. ten Hoeve, M. E. Rodriguez, M. Säflund, V. Michel, L. Magimel, A. Ripoll, T. Yu, M.-A. Hakimi, J. P. Saeij, D. M. Ozata, A. Barragan

This study identifies how Toxoplasma gondii uses GRA effectors to manipulate host signaling and chromatin accessibility, promoting macrophage migration and parasite dissemination.

bioRxiv · Feb 6, 2024 · PreprintMicrobiology

CRISPR-induced exon skipping of β-catenin reveals tumorigenic mutants driving distinct subtypes of liver cancer

H. Mou, J. Yue, Y. Jin, Z. Wang, Y. Gao, T. Janowitz, H. V. Meyer, A. Kucukural, J. E. Wilkinson, D. M. Ozata, S. Beyaz

This study shows CRISPR/Cas9 can induce exon skipping in β-catenin, creating gain-of-function mutations that drive distinct liver cancer subtypes in mice and are found in human HCC patients.

bioRxiv · Mar 27, 2022Cancer Biology

The conserved zinc-finger protein GTSF1helps PIWI proteins achieve their full catalytic potential

A. Arif, S. Bailey, N. Izumi, T. A. Anzelon, D. M. Ozata, C. Andersson, I. Gainetdinov, I. J. MacRae, Y. Tomari, P. D. Zamore

This study identifies GTSF1 as an auxiliary protein that enhances the catalytic activity of PIWI proteins by potentiating their weak piRNA-directed RNA cleavage.

bioRxiv · May 4, 2021 · PreprintBiochemistry

Dietary suppression of MHC-II expression in intestinal stem cells enhances intestinal tumorigenesis

S. Beyaz, J. Roper, M. E. Xifaras, K. E. Bauer-Rowe, I. Ergin, L. Dohnalova, M. Biton, K. Shekar, H. Mou, O. Eskiocak, D. M. Ozata, C. Chung, K. Papciak, M. Almeqdadi, M. Fein, , O. H. Yilmaz

The paper shows that a high fat diet reduces MHC-II expression in intestinal stem cells, promoting tumorigenesis by altering immune recognition.

bioRxiv · Sep 5, 2020Cancer Biology