Author

J. P. Souza

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

R. B. Martins· 2 shared T. M. Lima· 2 shared A. Fabro· 1 shared C. A. Fuzo· 1 shared D. B. Caetite· 1 shared D. C. Nascimento· 1 shared D. S. Zamboni· 1 shared E. A. Neto· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersImmunology

R. B. Martins

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Author profile →

2 papers

Recent·Most cited

Drug repurposing to face Covid-19: Celastrol, a potential leading drug capable of inhibiting SARS-CoV-2 replication and induced inflammation

C. A. Fuzo, R. B. Martins, T. F. C. Fraga-Silva, M. K. Amstalden, T. Canassa-DeLeo, J. P. Souza, T. M. Lima, L. H. Faccioli, S. C. Franca, V. L. D. Bonato, E. A. Neto, M. Dias-Baruffi

This paper identifies celastrol as a potential drug for treating Covid-19 by inhibiting SARS-CoV-2 replication and reducing IL-6 secretion in infected cells.

bioRxiv · Apr 20, 2021Immunology

Infection of human lymphomononuclear cells by SARS-CoV-2

M. C. Pontelli, I. A. Castro, R. B. Martins, F. P. Veras, L. La Serra, D. C. Nascimento, R. S. Cardoso, R. Rosales, T. M. Lima, J. P. Souza, D. B. Caetite, M. H. Lima, J. T. Kawahisa, M. C. Giannini, L. P. Bonjorno, , E. Arruda

This study investigates SARS-CoV-2 infection of human lymphomononuclear cells in vitro and in vivo, finding that monocytes, B cells, and T cells are susceptible to infection and viral replication.

bioRxiv · Jul 28, 2020Microbiology