Author

M. C. Pontelli

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 4 Organism:human· 3 Assay:bulk RNA-seq· 1 Organism:mouse· 1 Research Focus:variant calling· 1

Frequent Co-Authors

E. Arruda· 3 shared J. d. P. Souza· 3 shared D. S. Zamboni· 2 shared I. A. Castro· 2 shared R. M. M. Viana· 2 shared A. C. L. Coelho· 1 shared A. Fabro· 1 shared A. M. Ventura· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersMicrobiology

E. Arruda

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

In Vitro Inhibition of SARS-CoV-2 Infection by Bromhexine hydrochloride

R. Martins, I. Ferreira, D. M. Jorge, L. Almeida, J. d. P. Souza, M. C. Pontelli, I. A. Castro, T. Melquiades, R. M. Mendes Viana, D. S. Zamboni, P. Marcato, E. Arruda

This study shows bromhexine hydrochloride inhibits SARS-CoV-2 infection in vitro by targeting TMPRSS2, reducing viral entry and progeny without direct virucidal activity.

bioRxiv · Dec 23, 2022 · PreprintPharmacology & Toxicology

Vesicular stomatitis virus chimeras expressing the Oropouche virus glycoproteins elicit protective immune responses in mice.

S. H. Stubbs, M. C. Pontelli, N. MISHRA, C. Zhuo, J. d. P. Souza, R. M. M. Viana, W. I. H. Lipkin, D. Knipe, E. A. Arruda, S. P. J. Whelan

This paper develops a chimeric VSV expressing OROV glycoproteins that elicits neutralizing antibodies and reduces viral infection in mice.

bioRxiv · Feb 19, 2021Microbiology

The replication of the human respiratory syncytial virus in a T cell line has multiple ineffective steps

R. de Souza Cardoso, A. C. L. Coelho, B. L. S. de Jesus, B. C. Vitti, J. d. P. Souza, R. M. M. Viana, M. C. Pontelli, T. Murakami, A. M. Ventura, A. Ono, E. Arruda

This study shows that HRSV infection of CD4+ T cells is inefficient compared to epithelial cells, with reduced fusion, lower protein production, and altered viral trafficking.

bioRxiv · Dec 28, 2020Microbiology

Infection of human lymphomononuclear cells by SARS-CoV-2

M. C. Pontelli, I. A. Castro, R. B. Martins, F. P. Veras, L. La Serra, D. C. Nascimento, R. S. Cardoso, R. Rosales, T. M. Lima, J. P. Souza, D. B. Caetite, M. H. Lima, J. T. Kawahisa, M. C. Giannini, L. P. Bonjorno, , E. Arruda

This study investigates SARS-CoV-2 infection of human lymphomononuclear cells in vitro and in vivo, finding that monocytes, B cells, and T cells are susceptible to infection and viral replication.

bioRxiv · Jul 28, 2020Microbiology