Author

L. Gaucherand

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:comparative / phylogenetic analysis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

C. H. Rycroft· 2 shared A. Iyer· 1 shared B. K. Porter· 1 shared C. McCormick· 1 shared D. A. Khaperskyy· 1 shared D. C. Lee· 1 shared I. Gilabert· 1 shared J. M. Coffin· 1 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersMicrobiology

C. H. Rycroft

Mutual co-authors in cluster

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3 papers

Recent·Most cited

The cut site specificity of the influenza A virus endoribonuclease PA-X allows it to discriminate between host and viral mRNAs

L. Gaucherand, A. Iyer, I. Gilabert, C. H. Rycroft, M. M. Gaglia

The paper identifies GCUG tetramers in hairpin loops as PA-X cleavage sites, showing PA-X discriminates host from viral mRNAs by targeting GCUG-rich regions prevalent in host transcripts.

bioRxiv · Jul 8, 2022Microbiology

Recombinant Origin and Interspecies Transmission of a HERV-K(HML-2)-related Primate Retrovirus 1 With a Novel RNA Transport Element

Z. H. Williams, L. Gaucherand, D. C. Lee, S. M. Mostafa, J. Phelan, J. M. Coffin, W. E. Johnson

The paper identifies recent HML-2 provirus activity in rhesus macaques and shows interspecies transmission to gibbons, with a novel RNA transport element replacing the ancestral Rec-RcRE system.

bioRxiv · May 11, 2022Microbiology

The influenza A virus endoribonuclease PA-X usurps host mRNA processing machinery to limit host gene expression

L. Gaucherand, B. K. Porter, S. K. Schmaling, C. H. Rycroft, Y. Kevorkian, C. McCormick, D. A. Khaperskyy, M. Gaglia

This study identifies PA-X, an influenza A virus protein, as a factor that selectively targets host mRNAs for degradation by hijacking RNA splicing machinery.

bioRxiv · Oct 14, 2018Microbiology