Author

J. R. Enriquez

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 3 Physiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:cell type annotation· 3 Organism:human· 3 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Research Focus:metabolism & bioenergetics· 2 Assay:scRNA-seq· 2

Frequent Co-Authors

H. A. McCauley· 3 shared J. G. Sanchez· 3 shared J. M. Wells· 3 shared R. A. Lang· 2 shared A. Chakraborty· 1 shared A. L. Matthis· 1 shared A. M. Riedman· 1 shared B.-J. M. Webb-Robertson· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersCell Biology

H. A. McCauley

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Inhibition of the Eukaryotic Initiation Factor-2-α Kinase PERK Decreases Risk of Autoimmune Diabetes in Mice

C. Muralidharan, F. Huang, J. R. Enriquez, J. E. Wang, J. B. Nelson, T. Nargis, S. C. May, A. Chakraborty, K. T. Figatner, S. Navitskaya, C. M. Anderson, V. Calvo, D. Surguladze, M. J. Mulvihill, X. Yi, , R. G. Mirmira

This study shows that inhibiting PERK reduces autoimmune diabetes risk in mice by decreasing β cell immunogenicity and improving islet function.

bioRxiv · Oct 6, 2023Cell Biology

Enteroendocrine cells protect the stem cell niche by regulating crypt metabolism in response to nutrients

H. A. McCauley, A. M. Riedman, J. R. Enriquez, X. Zhang, M. Watanabe-Chailland, J. G. Sanchez, D. O. Kechele, E. F. Paul, K. Riley, C. Burger, R. A. Lang, J. M. Wells

This study shows that enteroendocrine cells regulate crypt metabolism and intestinal stem cell function by transmitting nutrient status to the stem cell niche.

bioRxiv · Oct 1, 2022Cell Biology

High fat diet initiates rapid adaptation of the intestine

J. R. Enriquez, H. A. McCauley, K. X. Zhang, J. G. Sanchez, G. T. Kalin, R. A. Lang, J. M. Wells

This study shows that a high fat diet rapidly alters intestinal epithelial cell function and composition within days, including stress responses and shifts in metabolic and absorptive capabilities.

bioRxiv · Mar 31, 2022Cell Biology

Enteroendocrine cells couple nutrient sensing to nutrient absorption by regulating ion transport

H. A. McCauley, A. L. Matthis, J. R. Enriquez, J. Nichol, J. G. Sanchez, W. J. Stone, N. Sundaram, M. A. Helmrath, M. H. Montrose, E. Aihara, J. M. Wells

This study identifies peptide YY as a regulator of ion-coupled nutrient absorption in the small intestine, showing its therapeutic potential for malabsorption.

bioRxiv · Apr 21, 2020Physiology