Author

J. Rasaiyaah

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Approach:comparative / phylogenetic analysis· 1 Assay:structural biology· 1

Frequent Co-Authors

G. J. Towers· 2 shared L. Zuliani-Alvarez· 2 shared B. H. Hahn· 1 shared C. Dickson· 1 shared C. Monit· 1 shared C. P. Tan· 1 shared C. Van Tulleken· 1 shared D. Fink· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersImmunology

G. J. Towers

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2 papers

Recent·Most cited

Macrophage activation of cGAS and TRIM5 distinguish pandemic and non-pandemic HIV

L. Zuliani-Alvarez, M. Larsen, J. Rasaiyaah, C. Monit, S. O. Perry, R. Sumner, S. McAlpine-Scott, C. Dickson, K. M. Rifat Faysal, L. Hilditch, R. Miles, F. Bibollet-Ruche, B. H. Hahn, T. Bocking, N. Pinotsis, , G. J. Towers

The paper compares pandemic HIV-1(M) and non-pandemic HIV strains, finding that non-pandemic strains activate cGAS and TRIM5 in myeloid cells, leading to antiviral responses and poor replication.

bioRxiv · Jan 21, 2022 · PreprintImmunology

HIV-1 Vpr antagonizes innate immune activation by targeting karyopherin-mediated NF-kB/IRF3 nuclear transport

H. Khan, R. P. Sumner, J. Rasaiyaah, C. P. Tan, M. T. Rodriguez-Plata, C. Van Tulleken, D. Fink, L. Zuliani-Alvarez, L. Thorne, D. Stirling, R. S. B. Milne, G. J. Towers

This study shows HIV-1 Vpr inhibits IRF3 and NF-κB nuclear transport by interacting with karyopherins, thereby evading innate immune activation and promoting HIV-1 replication in macrophages.

bioRxiv · Feb 22, 2020Microbiology