J. Rodriguez-Vita

This study identifies HAPLN1 as a driver of peritoneal metastasis in pancreatic cancer by enhancing tumor cell plasticity and immunomodulation.

This study shows that endothelial Rbpj promotes TAM education in EOC by regulating CXCL2, which drives CD44 expression and cholesterol depletion in TAMs, creating an immunosuppressive TME.

This study shows that deleting TSC22D4 in hepatocytes reduces liver damage in NASH by improving mitochondrial function and lipid metabolism.

This study identifies SEMA3C as a key driver of liver fibrosis by enhancing TGF-β signaling in hepatic stellate cells.

This study shows that different oils cause varying levels of peritoneal inflammation and macrophage depletion, with peanut oil causing severe chronic inflammation and olive oil promoting inflammation resolution.