Author

M. Sakurai

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 1 Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

J. Wu· 2 shared Y. Hu· 2 shared A. E. Jones· 1 shared A. Fischer· 1 shared A. M. Lambowitz· 1 shared A. Maida· 1 shared A. Mhamane· 1 shared A. Weider· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiochemistry

J. Wu

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Biochemical and structural insights into a 5' to 3' RNA ligase reveal a potential role in tRNA ligation

Y. Hu, V. A. Lopez, H. Xu, J. P. Pfister, B. Song, K. A. Servage, M. Sakurai, B. T. Jones, J. T. Mendell, T. Wang, J. Wu, A. M. Lambowitz, D. R. Tomchick, K. Pawlowski, V. S. Tagliabracci

This study identifies C12orf29 as an RNA ligase that ligates tRNA and alters tRNA levels in mice, with structural insights into its catalytic mechanism.

bioRxiv · Apr 24, 2024Biochemistry

RNA Sensing and Innate Immunity Constitutes a Barrier for Interspecies Chimerism

Y. Hu, H.-X. Sun, M. Sakurai, A. E. Jones, L. Liu, T. Cheng, C. Zheng, J. Li, B. Ravaux, Z. Luo, Y. Ding, T. Liu, Y. Wu, E. Chen, Z. Chen, , J. Wu

This study identifies RNA sensing and innate immunity in host embryos as a barrier to interspecies chimerism and shows that modifying host embryos can enhance human cell survival in chimeric embryos.

bioRxiv · Mar 7, 2023 · PreprintCell Biology

Hepatocyte-specific activity of TSC22D4 triggers progressive NAFLD by impairing mitochondrial function

G. Wolff, M. Sakurai, A. Mhamane, A. Maida, I. K. Deligiannis, K. Yin, P. Weber, A. Weider, M. Troullinaki, A. Zeigerer, M. Roden, N. Volk, T. Poth, T. Hackert, L. Wiedmann, , S. Herzig

This study shows that deleting TSC22D4 in hepatocytes reduces liver damage in NASH by improving mitochondrial function and lipid metabolism.

bioRxiv · Dec 17, 2021Physiology