Author

J. Samphire

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Assay:proteomics· 2 Organism:bacteria (other)· 1 Approach:biophysical modeling· 1 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Approach:statistical model· 1

Frequent Co-Authors

J. Spencer· 2 shared K. J. Heesom· 2 shared M. C. Galan· 2 shared P. A. Lewis· 2 shared Y. Takebayashi· 2 shared C. Gurr· 1 shared D. Alibhai· 1 shared E. Belmonte-Reche· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersMicrobiology

J. Spencer

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Small Molecule G-quadruplex Ligands are Antibacterial Candidates for Gram-negative Bacteria

Y. Takebayashi, J. Ramos-Soriano, Y. J. Jiang, J. Samphire, E. Belmonte-Reche, M. P. O'Hagan, C. Gurr, K. J. Heesom, P. A. Lewis, T. Samernate, P. Nonejuie, J. Spencer, M. C. Galan

The paper identifies a G-quadruplex ligand, L9, as a potential antibacterial agent against multi-drug resistant E. coli, showing superior activity and distinct mechanism compared to existing ligands.

bioRxiv · Sep 1, 2022 · PreprintMicrobiology

Green Fluorescent Carbon Dots as Targeting Probes for LED-Dependent Bacterial Killing

Y. Takebayashi, J. Samphire, S. A. Hill, N. Hill, K. J. Heesom, P. A. Lewis, D. Alibhai, E. C. Bragginton, J. Dorh, N. Dorh, J. Spencer, M. C. Galan

This paper demonstrates that green fluorescent carbon dots can label and kill Gram-positive and Gram-negative bacteria when combined with LED light exposure.

bioRxiv · Mar 26, 2021Microbiology