Author

M. C. Galan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biochemistry· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:proteomics· 2 Organism:bacteria (other)· 1 Approach:biophysical modeling· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Assay:fluorescence / live-cell microscopy· 1

Frequent Co-Authors

J. Samphire· 2 shared J. Spencer· 2 shared K. J. Heesom· 2 shared P. A. Lewis· 2 shared Y. Takebayashi· 2 shared A. Marchesi· 1 shared A. P. Green· 1 shared A. P. Mattey· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersMicrobiology

J. Samphire

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Small Molecule G-quadruplex Ligands are Antibacterial Candidates for Gram-negative Bacteria

Y. Takebayashi, J. Ramos-Soriano, Y. J. Jiang, J. Samphire, E. Belmonte-Reche, M. P. O'Hagan, C. Gurr, K. J. Heesom, P. A. Lewis, T. Samernate, P. Nonejuie, J. Spencer, M. C. Galan

The paper identifies a G-quadruplex ligand, L9, as a potential antibacterial agent against multi-drug resistant E. coli, showing superior activity and distinct mechanism compared to existing ligands.

bioRxiv · Sep 1, 2022 · PreprintMicrobiology

Carbon Dot-based Fluorescent Antibody Nanoprobes as Brain Tumour Glioblastoma Diagnostics.

M. Ghirardello, R. Shyam, X. Liu, T. Garcia Millan, I. Sittel, J. Ramos Soriano, M. C. Galan, K. Kurian

This paper develops carbon dot-based fluorescent antibody nanoprobes for glioblastoma diagnostics, showing they are robust, photostable, and applicable in clinical settings.

bioRxiv · Nov 29, 2021Immunology

Green Fluorescent Carbon Dots as Targeting Probes for LED-Dependent Bacterial Killing

Y. Takebayashi, J. Samphire, S. A. Hill, N. Hill, K. J. Heesom, P. A. Lewis, D. Alibhai, E. C. Bragginton, J. Dorh, N. Dorh, J. Spencer, M. C. Galan

This paper demonstrates that green fluorescent carbon dots can label and kill Gram-positive and Gram-negative bacteria when combined with LED light exposure.

bioRxiv · Mar 26, 2021Microbiology

In vitro biosynthesis of poly-β-1,4-glucan derivatives using a promiscuous glycosyltransferase

G. S. Bulmer, A. P. Mattey, F. Parmeggiani, R. Williams, H. Ledru, A. Marchesi, L. S. Seibt, P. Both, K. Huang, M. C. Galan, S. Flitsch, A. P. Green, J. M. van Munster

This study uses a promiscuous glycosyltransferase to synthesize cello-oligosaccharides and their derivatives, enabling tailored glycan structures for biotechnological applications.

bioRxiv · Feb 14, 2020 · PreprintBiochemistry