Cryo-EM Structures of the N501Y SARS-CoV-2 Spike Protein in Complex with ACE2 and Two Potent Neutralizing Antibodies
X. Zhu, D. Mannar, S. S. Srivastava, A. Berezuk, J.-P. Demers, J. Saville, K. Leopold, W. Li, D. S. Dimitrov, K. Tuttle, S. Zhou, S. Chittori, S. Subramaniam
The paper presents cryo-EM structures of the N501Y SARS-CoV-2 spike protein complex with ACE2 and neutralizing antibodies, showing increased ACE2 binding affinity and retained epitopes.
bioRxiv · Jan 11, 2021 · PreprintBiophysics