Author

J. Seurat

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 3

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:statistical model· 3 Organism:bacteria (other)· 1 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

J. S. Weitz· 2 shared L. Debarbieux· 2 shared B. Gaborieau· 1 shared C. Mulet· 1 shared C. N. N. Minh· 1 shared E. Evrard· 1 shared F. Haddad· 1 shared J. Guedj· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMicrobiology

J. S. Weitz

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Design, optimization, and inference of biphasic decay of infectious virus particles

J. Seurat, K. R. Gerbino, J. R. Meyer, J. M. Borin, J. S. Weitz

This paper develops methods to detect and optimize sampling for multiphasic virus decay, applying them to show that 94% of phage ΦD9 decays 16-fold faster than the remaining population.

Journal of Theoretical Biology · Mar 1, 2025Peer-reviewedMicrobiology

Macrophage-induced reduction of bacteriophage density limits the efficacy of in vivo pulmonary phage therapy

S. Zborowsky, J. Seurat, Q. Balacheff, S. Ecomard, C. Mulet, C. N. N. Minh, M. Titecat, E. Evrard, R. A. Rodriguez-Gonzalez, J. Marchi, J. S. Weitz, L. Debarbieux

This study shows that macrophages reduce bacteriophage density in the lungs, limiting the effectiveness of phage therapy in treating Pseudomonas aeruginosa pneumonia.

bioRxiv · Jan 16, 2024Microbiology

Combination of in vivo phage therapy data with in silico model highlights key parameters for treatment efficacy

R. Delattre, J. Seurat, F. Haddad, T.-T. Nguyen, B. Gaborieau, R. Kane, N. Dufour, J.-D. Ricard, J. Guedj, L. Debarbieux

The paper combines in vivo phage therapy data with an in silico model to identify key parameters affecting treatment efficacy in bacterial pneumonia.

bioRxiv · Mar 4, 2021Microbiology