Author

J. Shangguan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Assay:fluorescence / live-cell microscopy· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

D. A. Drummond· 1 shared D. Heineck· 1 shared D. Kahan· 1 shared F. Civitci· 1 shared J. A. Riback· 1 shared J. Kenison· 1 shared J. R. Sachleben· 1 shared M. J. Rames· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperBiophysics

D. A. Drummond

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Hundreds of myosin 10s are pushed to the tips of filopodia and could cause traffic jams on actin

J. Shangguan, R. S. Rock

The paper quantifies Myo10 molecule numbers in filopodia, revealing high concentrations that exceed actin binding sites and correlate with filopodial dynamics.

bioRxiv · Jun 26, 2023Cell Biology

Sequential Activation and Local Unfolding Control Poly(A)-Binding Protein Condensation

R. Chen, D. Kahan, J. Shangguan, J. R. Sachleben, J. A. Riback, D. A. Drummond, T. Sosnick

This study uses HDX-MS to reveal that Pab1 condensation involves sequential activation of its RRMs through partial unfolding, driven by thermodynamic specificity.

bioRxiv · Sep 21, 2022 · PreprintBiophysics

Multiplexed and millimeter-scale fluorescence nanoscopy of cells and tissue sections via prism-illumination and microfluidics-enhanced DNA-PAINT

M. J. Rames, J. Kenison, D. Heineck, F. Civitci, M. Szczepaniak, T. Zheng, J. Shangguan, Y. Zhang, S. Esener, X. Nan

This paper introduces PRIME-PAINT, a method for multiplexed fluorescence nanoscopy with millimeter-scale field-of-view and high resolution, demonstrating its use on biological samples.

bioRxiv · Aug 7, 2022 · PreprintBiophysics