Semaphorin 3G exacerbates joint inflammation through the accumulation and proliferation of macrophages in the synovium
J. Shoda, S. Tanaka, K. Etori, K. Hattori, T. Kasuya, K. Ikeda, Y. Maezawa, A. Suto, K. Suzuki, J. Nakamura, Y. Maezawa, M. Takemoto, C. Betsholtz, K. Yokote, S. Ohtori, H. Nakajima
This study identifies Semaphorin 3G as a factor that worsens joint inflammation by promoting macrophage accumulation and proliferation in RA synovium.
bioRxiv · Feb 12, 2022Pathology