Author

M. Farina

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:cell type annotation· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:development & morphogenesis· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

A. Dunbar· 2 shared A. Karzai· 2 shared J. L. Yang· 2 shared R. Koche· 2 shared W. Xiao· 2 shared Y. Park· 2 shared A. Krishnan· 1 shared A. Nazir· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersCancer Biology

A. Dunbar

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Jak2V617F Reversible Activation Shows an Essential Requirement for Jak2V617F in Myeloproliferative Neoplasms

A. Dunbar, R. L. Bowman, Y. Park, F. Izzo, R. M. Myers, A. Karzai, W. Jun Kim, I. Fernandez Maestre, M. R. Waarts, A. Nazir, W. Xiao, M. Brodsky, M. Farina, L. Cai, S. F. Cai, , R. L. Levine

This study shows that reversible activation of Jak2V617F in a mouse model demonstrates its essential role in myeloproliferative neoplasms and highlights the therapeutic potential of mutant-specific JAK2 inhibition.

bioRxiv · May 18, 2022 · PreprintCancer Biology

CXCL8/CXCR2 signaling mediates bone marrow fibrosis and represents a therapeutic target in myelofibrosis

A. Dunbar, D. Kim, M. Lu, M. Farina, J. L. Yang, Y. Park, F. Gobbo, P. Verachi, F. Martelli, A. Karzai, W. Xiao, L. Xia, N. Elmansy, M. Kleppe, Z. Chen, , R. Hoffman

This study identifies CXCL8/CXCR2 signaling as a driver of bone marrow fibrosis in myelofibrosis and shows its therapeutic potential through genetic and pharmacologic inhibition.

bioRxiv · Dec 8, 2021Cancer Biology

Disruption of augmin-mediated microtubule nucleation in neural stem cells causes p53-dependent apoptosis and aborts brain development.

R. Viais, S. Watanabe, M. Villamor, L. Palenzuela, C. Lacasa, M. Farina, J. Luders

bioRxiv · Nov 18, 2020Cell Biology

Membrane Elastic Properties During Neural Progenitor/Neural Stem Cell Differentiation

J. Soares, G. R. d. S. Araujo, C. Santana, D. Matias, V. Moura-Neto, M. Farina, S. Frases, N. B. Viana, L. Romao, H. M. Nussenzveig, B. Pontes

The paper measures membrane tension and bending modulus during neural stem cell differentiation into neurons, astrocytes, and oligodendrocytes, revealing distinct mechanical changes correlated with morphological and molecular transitions.

Cells · May 26, 2020Peer-reviewedBiophysics