Author

A. Boire

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Assay:CITE-seq· 1 Research Focus:clustering· 1 Approach:deep learning· 1

Frequent Co-Authors

A. Balan· 1 shared A. Cercek· 1 shared A. L. Ho· 1 shared A. Luthra· 1 shared A. N. Shoushtari· 1 shared A. Osman· 1 shared A. Safonov· 1 shared A. Stortchevoi· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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1 shared paperCancer Biology

A. Balan

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Author profile →

3 papers

Recent·Most cited

A generative reference grammar of healthy TCR repertoires reveals cancer-associated immune remodeling

A. Balan, Y. Elhanati, K. E. Meza Landeros, M. De Almeida Mendes, J. Lai, S. S. A. Zaidi, M. Unal, B. Y. S. Kim, C.-H. G. Lucas, E. Runco, V. K. Puduvalli, J. Gantchev, C. A. Whittaker, P. Sharma, V. Tabar, , R. Karchin

CRAFT, a transformer model, learns a generative grammar of healthy TCR repertoires to detect cancer-associated immune remodeling through structured deviations in sequence space.

bioRxiv · Jun 20, 2026 · PreprintCancer Biology

Leptomeningeal anti-tumor immunity follows unique signaling principles

J. Remsik, X. Tong, R. Z. Kunes, M. J. Li, A. Osman, K. Chabot, U. Sener, J. A. Wilcox, D. Isakov, J. Snyder, T. Bale, R. Chaligne, D. D. Pe'er, A. Boire

The paper investigates IFN-γ signaling in leptomeningeal metastasis and shows its role in recruiting myeloid cells to control tumor growth.

bioRxiv · Mar 17, 2023 · PreprintCancer Biology

Genomic characterization of metastatic patterns from prospective clinical sequencing of 25,000 patients

B. Nguyen, C. Fong, A. Luthra, S. A. Smith, R. G. DiNatale, S. Nandakumar, H. Walch, W. K. Chatila, R. Madupuri, R. Kundra, C. M. Bielski, B. Mastrogiacomo, A. Boire, S. Chandarlapaty, K. Ganesh, , Varghes

The paper analyzes genomic data from 25,000 patients to identify associations between genomic alterations and metastatic patterns across 50 tumor types, finding chromosomal instability correlates with metastatic burden in some cancers.

bioRxiv · Jun 28, 2021Cancer Biology