Author

T. Bale

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Boire· 1 shared A. Osman· 1 shared B. G. Neel· 1 shared C. Davis· 1 shared C. Iltis· 1 shared C. Zhang· 1 shared D. D. Pe'er· 1 shared D. Isakov· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

A. Boire

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Leptomeningeal anti-tumor immunity follows unique signaling principles

J. Remsik, X. Tong, R. Z. Kunes, M. J. Li, A. Osman, K. Chabot, U. Sener, J. A. Wilcox, D. Isakov, J. Snyder, T. Bale, R. Chaligne, D. D. Pe'er, A. Boire

The paper investigates IFN-γ signaling in leptomeningeal metastasis and shows its role in recruiting myeloid cells to control tumor growth.

bioRxiv · Mar 17, 2023 · PreprintCancer Biology

Dual inhibition of SHP2 and autophagy suppresses NF1-associated Malignant Peripheral Nerve Sheath Tumors

S. Farouk Sait, K.-h. Tang, S. Angus, R. Brown, D. Sun, X. Xie, C. Iltis, M. Lien, N. Socci, T. Bale, C. Davis, S. A. H. Dixon, C. Zhang, D. W. Clapp, B. G. Neel, L. F. Parada

This study shows that combining SHP2 and autophagy inhibition effectively suppresses NF1-associated MPNSTs in mouse models, suggesting a potential new treatment approach.

bioRxiv · Aug 18, 2022 · PreprintCancer Biology