Author

J. Stolk

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

A. Delaunay-Moisan· 1 shared A. Edelman· 1 shared A. Golec· 1 shared A. Hinzpeter· 1 shared A. Premchandar· 1 shared B. Chevalier· 1 shared B. Martinez-Delgado· 1 shared D. A. Lomas· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCell Biology

A. Delaunay-Moisan

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2 papers

Recent·Most cited

Keratin 8 is a scaffolding and regulatory protein of ERAD complexes

I. M. Pranke, B. Chevalier, A. Premchandar, N. Baatallah, K. F. Tomaszewski, S. Bitam, D. Tondelier, A. Golec, J. Stolk, G. L. Lukacs, P. S. Hiemstra, M. Dadlez, D. A. Lomas, J. A. Irving, A. Delaunay-Moisan, , A. Edelman

This study shows that Keratin 8 modulates ERAD complexes, enhancing degradation of misfolded proteins like Z-A1AT and F508del-CFTR, and suggests targeting K8 for therapeutic intervention in A1ATD.

bioRxiv · Feb 1, 2022Cell Biology

Polymerization of misfolded protein lowers CX3CR1 expression in human PBMCs

S. Tumpara, M. Ballmaier, S. Wrenger, M. König, M. Lehmann, R. Lichtinghagen, B. Martinez-Delgado, D. DeLuca, N. Jedicke, T. Welte, M. Fromme, P. Strnad, J. Stolk, S. Janciauskiene

This study shows that polymerized misfolded Z-AAT protein reduces CX3CR1 expression on human PBMCs, suggesting a role for extracellular misfolded proteins in immune regulation.

bioRxiv · Nov 24, 2020Cell Biology