Nucleotide Biosynthesis Links Glutathione Metabolism to Ferroptosis Sensitivity
A. Tarangelo, J. T. Kim, J. Z. Long, S. J. Dixon
The paper shows that p53 inhibition of nucleotide metabolism reduces ferroptosis by preserving glutathione levels through RNR suppression.
Life Science Alliance · Jan 24, 2022Peer-reviewedCancer Biology