Author

J. T. Manning

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 3 Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 2 Organism:rat· 2 Research Focus:benchmarking· 1

Frequent Co-Authors

J. Maruyama· 3 shared S. Paessler· 3 shared H. Ji· 2 shared H. Zhou· 2 shared L. Kerwin· 2 shared M. Brunswick· 2 shared R. D. Allen· 2 shared A. Ledesma· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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3 shared papersMicrobiology

J. Maruyama

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3 papers

Recent·Most cited

Machupo virus with mutations in the transmembrane domain and glycosylation sites is attenuated and immunogenic in animal models of Bolivian Hemorrhagic Fever

E. Mantlo, J. Maruyama, J. T. Manning, T. G. Wanninger, C. Huang, J. N. Smith, M. Patterson, S. Paessler, T. Koma

This paper attenuates Machupo virus by mutating glycosylation sites and a transmembrane domain residue, showing attenuation in animal models and protective efficacy against wild-type virus.

bioRxiv · Dec 2, 2021 · PreprintMicrobiology

Protective Effects of STI-2020 Antibody Delivered Post-Infection by the Intranasal or Intravenous Route in a Syrian Golden Hamster COVID-19 Model

Y. Fu, J. Maruyama, A. Singh, R. Lim, A. Ledesma, D. Lee, L. Rivero-Nava, J. Ko, I. Rivera, R. A. Sattler, J. T. Manning, L. Kerwin, H. Zhou, M. Brunswick, D. Bresson, , R. D. Allen

This study evaluates the efficacy of STI-2020 antibody delivered post-infection via intranasal or intravenous routes in a hamster model of COVID-19, showing reduced disease severity and duration.

bioRxiv · Oct 28, 2020 · PreprintMicrobiology

Discovery and Development of Human SARS-CoV-2 Neutralizing Antibodies using an Unbiased Phage Display Library Approach

X. Cao, J. Maruyama, H. Zhou, L. Kerwin, R. Sattler, J. T. Manning, S. Johnson, S. Richards, Y. Li, W. Shen, B. Blair, N. Du, K. Morais, K. Lawrence, L. Lu, , R. D. Allen

This study identifies and develops human SARS-CoV-2 neutralizing antibodies using a phage display library, showing their efficacy in vivo against the virus.

bioRxiv · Sep 27, 2020 · PreprintMicrobiology