Author

L. Kerwin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 4 Approach:experimental assay· 4 Organism:human· 3 Assay:proteomics· 3 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:benchmarking· 1 Organism:rat· 1

Frequent Co-Authors

H. Ji· 4 shared H. Zhou· 4 shared J. Maruyama· 3 shared S. Johnson· 3 shared Y. Fu· 3 shared Y. Zhang· 3 shared A. Ledesma· 2 shared A. Singh· 2 shared

Activity by Year

2020-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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4 shared papersMicrobiology

H. Ji

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Discovery of a SARS-CoV-2 Broadly-Acting Neutralizing Antibody with Activity against Omicron and Omicron + R346K Variants

J. A. Duty, T. A. Kraus, H. Zhou, Y. Zhang, N. Shaabani, S. Yildiz, N. Du, A. Singh, L. Miorin, D. Li, K. Stegman, S. I. Ophir, X. Cao, K. Atanasoff, R. Lim, , R. Allen

This paper identifies a broadly neutralizing antibody, STI-9167, effective against SARS-CoV-2 variants including Omicron and Omicron + R346K, and describes its development for clinical trials.

bioRxiv · Jan 19, 2022 · PreprintMicrobiology

Protective Effects of STI-2020 Antibody Delivered Post-Infection by the Intranasal or Intravenous Route in a Syrian Golden Hamster COVID-19 Model

Y. Fu, J. Maruyama, A. Singh, R. Lim, A. Ledesma, D. Lee, L. Rivero-Nava, J. Ko, I. Rivera, R. A. Sattler, J. T. Manning, L. Kerwin, H. Zhou, M. Brunswick, D. Bresson, , R. D. Allen

This study evaluates the efficacy of STI-2020 antibody delivered post-infection via intranasal or intravenous routes in a hamster model of COVID-19, showing reduced disease severity and duration.

bioRxiv · Oct 28, 2020 · PreprintMicrobiology

Discovery and Development of Human SARS-CoV-2 Neutralizing Antibodies using an Unbiased Phage Display Library Approach

X. Cao, J. Maruyama, H. Zhou, L. Kerwin, R. Sattler, J. T. Manning, S. Johnson, S. Richards, Y. Li, W. Shen, B. Blair, N. Du, K. Morais, K. Lawrence, L. Lu, , R. D. Allen

This study identifies and develops human SARS-CoV-2 neutralizing antibodies using a phage display library, showing their efficacy in vivo against the virus.

bioRxiv · Sep 27, 2020 · PreprintMicrobiology

A Targeted Vaccine against COVID-19: S1-Fc Vaccine Targeting the Antigen-Presenting Cell Compartment Elicits Protection against SARS-CoV-2 Infection

A. Herrmann, J. Maruyama, C. Yue, C. Lahtz, H. Zhou, L. Kerwin, W. Guo, Y. Zhang, W. Soo Hoo, S. Yei, S. Kwon, Y. Fu, S. Johnson, A. Ledesma, Y. Zhuang, , H. Ji

This paper develops a S1-Fc vaccine targeting antigen-presenting cells, showing it elicits protective anti-SARS-CoV-2 IgG and T cell responses, with high protection at low doses.

bioRxiv · Jun 29, 2020 · PreprintMicrobiology