Author

A. Ledesma

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:benchmarking· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1 Organism:rat· 1

Frequent Co-Authors

H. Ji· 2 shared H. Zhou· 2 shared J. Maruyama· 2 shared L. Kerwin· 2 shared Y. Fu· 2 shared A. Herrmann· 1 shared A. Singh· 1 shared C. Lahtz· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersMicrobiology

H. Ji

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Protective Effects of STI-2020 Antibody Delivered Post-Infection by the Intranasal or Intravenous Route in a Syrian Golden Hamster COVID-19 Model

Y. Fu, J. Maruyama, A. Singh, R. Lim, A. Ledesma, D. Lee, L. Rivero-Nava, J. Ko, I. Rivera, R. A. Sattler, J. T. Manning, L. Kerwin, H. Zhou, M. Brunswick, D. Bresson, , R. D. Allen

This study evaluates the efficacy of STI-2020 antibody delivered post-infection via intranasal or intravenous routes in a hamster model of COVID-19, showing reduced disease severity and duration.

bioRxiv · Oct 28, 2020 · PreprintMicrobiology

A Targeted Vaccine against COVID-19: S1-Fc Vaccine Targeting the Antigen-Presenting Cell Compartment Elicits Protection against SARS-CoV-2 Infection

A. Herrmann, J. Maruyama, C. Yue, C. Lahtz, H. Zhou, L. Kerwin, W. Guo, Y. Zhang, W. Soo Hoo, S. Yei, S. Kwon, Y. Fu, S. Johnson, A. Ledesma, Y. Zhuang, , H. Ji

This paper develops a S1-Fc vaccine targeting antigen-presenting cells, showing it elicits protective anti-SARS-CoV-2 IgG and T cell responses, with high protection at low doses.

bioRxiv · Jun 29, 2020 · PreprintMicrobiology