Author

J. Tainer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. B. Maitra· 1 shared A. Bacolla· 1 shared A. S. Holehouse· 1 shared B. A. Townley· 1 shared B.-F. Pan· 1 shared C.-F. Li· 1 shared C.-L. Tsai· 1 shared D. F. Wozniak· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperCancer Biology

A. B. Maitra

Mutual co-authors in cluster

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2 papers

Recent·Most cited

A condensate forming tether for lariat debranching enzyme is defective in non-photosensitive trichiothiodystrophy

B. A. Townley, L. Buerer, A. Bacolla, T. Rusanov, N. Schmidt, S. N. Srivatsan, N. E. Clark, F. Mansoori, R. A. Sample, J. R. Brickner, D. McDonald, M.-S. Tsai, M. Walter, D. F. Wozniak, A. S. Holehouse, , N. Mosammaparast

This study identifies TTDN1's role in linking intron lariat processing to the spliceosome, showing its defect causes splicing and gene expression issues in NP-TTD.

bioRxiv · Nov 3, 2022 · PreprintBiochemistry

Nardilysin-Regulated Scission Mechanism Activates Polo-like Kinase 3 to Suppress the Development of Pancreatic Cancer

J. Fu, J. Li, C.-F. Li, C.-L. Tsai, W. Yin, J. Hou, P. Chen, Y. Cao, Y. Kang, Y. Sun, X. Xia, K. Furukawa, Y. Lu, M. Wu, Q. Huang, , P. Chiao

The paper identifies a post-translational mechanism where Nardilysin cleaves Plk3 to generate an active form that suppresses pancreatic cancer development and metastasis.

bioRxiv · Jul 28, 2022Cancer Biology