Author

M.-S. Tsai

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Microbiology· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Approach:statistical model· 3 Research Focus:chromatin & epigenetic regulation· 2 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

K. Gallagher· 2 shared W. J. Chazin· 2 shared A. Bacolla· 1 shared A. D'Souza· 1 shared A. S. Holehouse· 1 shared A. Topolska-Wos· 1 shared B. A. Townley· 1 shared C. D. Buesching· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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2 shared papersBiophysics

K. Gallagher

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Population genetic analyses of longitudinal vaginal microbiome reveal racioethnic evolutionary dynamics and prevailing positive selection of Lactobacillus adhesins

X. Wei, M.-S. Tsai, L. Liang, L. Jiang, C.-J. Hung, L. Jelliffe-Pawlowski, L. Rand, M. Snyder, C. Jiang

This study analyzes longitudinal vaginal microbiome data from diverse ethnic groups, revealing ethnic signatures in microbial diversity, community states, and evolutionary dynamics, with Lactobacillus adhesins showing positive selection.

bioRxiv · Oct 11, 2023 · PreprintMicrobiology

Structure of RADX and mechanism for regulation of RAD51 nucleofilaments

S. Balakrishnan, M. Adolph, M.-s. Tsai, K. Gallagher, D. Cortez, W. J. Chazin

This paper investigates the structure and mechanism of RADX, a negative regulator of RAD51 nucleofilaments, showing it caps and restricts RAD51 filament growth to regulate replication fork reversal.

bioRxiv · Sep 19, 2023 · PreprintBiophysics

A condensate forming tether for lariat debranching enzyme is defective in non-photosensitive trichiothiodystrophy

B. A. Townley, L. Buerer, A. Bacolla, T. Rusanov, N. Schmidt, S. N. Srivatsan, N. E. Clark, F. Mansoori, R. A. Sample, J. R. Brickner, D. McDonald, M.-S. Tsai, M. Walter, D. F. Wozniak, A. S. Holehouse, , N. Mosammaparast

This study identifies TTDN1's role in linking intron lariat processing to the spliceosome, showing its defect causes splicing and gene expression issues in NP-TTD.

bioRxiv · Nov 3, 2022 · PreprintBiochemistry

Two Interaction Surfaces between XPA and RPA Organize the Preincision Complex in Nucleotide Excision Repair

M. Kim, H. S. Kim, A. D'Souza, K. Gallagher, E. Jeong, A. Topolska-Wos, K. Ogorodnik Le Meur, C.-L. Tsai, M.-S. Tsai, M. Kee, J. A. Tainer, J.-E. Yeo, W. J. Chazin, O. D. Scharer

The paper investigates two interaction surfaces between XPA and RPA in the preincision complex of nucleotide excision repair, showing their distinct roles in complex assembly and NER activity.

bioRxiv · Mar 1, 2022Biochemistry

Patterns of Mustelid gammaherpesvirus 1 (MusGHV-1) genital reactivation linked to stressors in adult European badgers (Meles meles)

M.-s. Tsai, S. Francois, C. Newman, D. W. Macdonald, C. D. Buesching

This study links stressors to MusGHV-1 genital reactivation in European badgers, showing age, social structure, and environmental factors influence viral reactivation patterns.

bioRxiv · Jan 19, 2021Microbiology