Author

J. ten Hoeve-Scott

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

K. Tharp· 2 shared V. Weaver· 2 shared A. Combes· 1 shared A. Dillin· 1 shared A. E. Lefebvre· 1 shared A. Richards· 1 shared B. Samad· 1 shared C. Bertozzi· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCell Biology

K. Tharp

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2 papers

Recent·Most cited

The microenvironment dictates glycocalyx construction and immune surveillance

K. Tharp, S. Park, G. A. Timblin, A. Richards, J. Berg, N. Twells, N. M. Riley, E. Peltan, D. J. Shon, E. Stevenson, C. K. Tsui, F. Palomba, A. E. Lefebvre, R. Soens, N. Ayad, , V. Weaver

This study shows that the physical properties of the microenvironment influence glycocalyx composition and immune surveillance in vitro using physiologically relevant models.

bioRxiv · Jun 23, 2023 · PreprintCell Biology

Myeloid mechano-metabolic programming restricts anti-tumor immunity

K. Tharp, K. Kersten, O. Maller, G. Timblin, C. Stashko, F. Canale, M.-K. Hayward, I. Berestjuk, J. ten Hoeve-Scott, B. Samad, R. Geiger, A. Combes, V. Weaver

This study shows that fibrotic tumor microenvironments impair anti-tumor immunity through myeloid cell-driven metabolic changes that hinder CD8+ T cell function.

bioRxiv · Jul 14, 2022 · PreprintCancer Biology