Author

G. Timblin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Organism:human· 1

Frequent Co-Authors

C. Stashko· 2 shared A. Combes· 1 shared A. Dillin· 1 shared A. Dunn· 1 shared A. L. Richards· 1 shared A. S. Moore· 1 shared B. Ford· 1 shared B. Samad· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersCancer Biology

C. Stashko

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2 papers

Recent·Most cited

Myeloid mechano-metabolic programming restricts anti-tumor immunity

K. Tharp, K. Kersten, O. Maller, G. Timblin, C. Stashko, F. Canale, M.-K. Hayward, I. Berestjuk, J. ten Hoeve-Scott, B. Samad, R. Geiger, A. Combes, V. Weaver

This study shows that fibrotic tumor microenvironments impair anti-tumor immunity through myeloid cell-driven metabolic changes that hinder CD8+ T cell function.

bioRxiv · Jul 14, 2022 · PreprintCancer Biology

Adhesion-mediated mechanosignaling forces mitohormesis

K. M. Tharp, R. Higuchi-Sanabria, G. Timblin, B. Ford, C. Garzon-Coral, C. Schneider, J. M. Muncie, C. Stashko, J. Daniele, A. S. Moore, P. Frankino, S. Manoli, H. Shao, A. L. Richards, K.-H. Chen, , V. M. Weaver

The paper shows that adhesion-mediated mechanosignaling activates a mitochondrial stress response through SLC9A1 and HSF1, altering mitochondrial function in aging and cancer.

bioRxiv · Mar 6, 2020Cell Biology