Author

J. Tian

McGill University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 6 Cancer Biology· 6 Microbiology· 5 Ecology· 3 Immunology· 3 Pharmacology & Toxicology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 26 Organism:mouse· 11 Research Focus:host-pathogen & immune response· 9 Organism:human· 8 Research Focus:drug response / drug discovery· 7 Assay:bulk RNA-seq· 5 Research Focus:cell type annotation· 5 Research Focus:cancer & tumor microenvironment· 4

Frequent Co-Authors

Y. Zhang· 4 shared Z. Li· 4 shared L. Lu· 3 shared Z. Chen· 3 shared C. Ren· 2 shared C. Zhang· 2 shared D. L. Kaufman· 2 shared F. Kang· 2 shared

Activity by Year

2017-2026 · peak 12/yr

Co-Author Collaboration Network

10 top collaborators · 7 mutual co-author links

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4 shared papersMicrobiology

Y. Zhang

Mutual co-authors in cluster

Author profile →

32 papers

Recent·Most cited

BioengineeringbioRxivJan 17, 2020

Developing an endogenous quorum-sensing based CRISPRi circuit for autonomous and tunable dynamic regulation of multiple targets in industrial Streptomyces

J. Tian, G. Yang, Y. Gu…·W. Jiang

This paper develops an endogenous quorum-sensing based CRISPRi circuit (EQCi) to dynamically regulate multiple targets in Streptomyces, achieving higher rapamycin titers without affecting cell growth.

DOI 10.1093/nar/gkaa602

bacteria (other)genetic perturbation / CRISPR

𝕏 PostBluesky

Evolutionary BiologyNature Ecology & EvolutionPeer-reviewedApr 28, 2017

Optimization of lag phase shapes the evolution of a bacterial enzyme

B. V. Adkar, M. Manhart, S. Bhattacharyya…·E. I. Shakhnovich

This study examines how mutations in E. coli's Adenylate Kinase affect growth phases, revealing that catalytic capacity optimizes lag time while growth rates are less affected.

DOI 10.1038/s41559-017-0149

E. coliwhole-genome sequencing

𝕏 PostBluesky