Author

J. Toh

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Assay:bulk RNA-seq· 1 Approach:comparative / phylogenetic analysis· 1 Approach:experimental assay· 1 Assay:imaging· 1 Approach:microscopy & imaging analysis· 1 Organism:non-human primate· 1

Frequent Co-Authors

`Najla Nasr· 1 shared A. Craig· 1 shared A. Di Re· 1 shared A. N. Harman· 1 shared C. A. Blish· 1 shared C. A. Moxon· 1 shared C.-H. Toh· 1 shared D. C. Douek· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperImmunology

`Najla Nasr

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Author profile →

3 papers

Recent·Most cited

Systems immunology of transcriptional responses to viral infection identifies conserved antiviral pathways across macaques and humans

K. Ratnasiri, H. Zheng, J. Toh, Z. Yao, V. Duran, M. Donato, M. Roederer, M. Kamath, J.-P. M. Todd, M. Gagne, K. E. Foulds, J. R. Francica, K. S. Corbett, D. C. Douek, R. A. Seder, , P. Khatri

The paper identifies conserved antiviral pathways across macaques and humans using transcriptomic data from viral infections, showing shared and virus-specific responses that inform pandemic preparedness.

bioRxiv · Jun 22, 2023Immunology

An in situ quantitative map of initial human colorectal HIV transmission

H. Baharlou, N. P. Canete, E. E. Vine, k. hu, D. Yuan, K. J. Sandgren, K. M. Bertram, `Najla Nasr, J. W. Rhodes, M. Gosselink, A. Di Re, F. Reza, G. Ctercteko, N. ` Pathma-Nathan, G. Collins, , A. N. Harman

This study quantifies HIV transmission dynamics in human colorectal tissue, showing HIV localizes to mucosal dendritic cells and submucosal macrophages rather than CD4+ T-cells.

bioRxiv · Apr 30, 2022Immunology

Parasite histones mediate leak and coagulopathy in cerebral malaria

C. A. Moxon, Y. Alhamdi, J. Storm, J. Toh, J. Y. Ko, G. Murphy, T. Taylor, K. Seydel, S. Kampondeni, M. Potchen, J. O'Donnell, N. O'Regan, G. Wang, G. Garcia-Cardena, M. Molyneux, , C.-H. Toh

This study shows parasite histones contribute to coagulopathy and vascular leak in cerebral malaria, leading to brain swelling and poor outcomes.

bioRxiv · Mar 20, 2019 · PreprintMicrobiology