J. Tseng

The carnivoran adaptive landscape reveals functional trade-offs among the skull, appendicular, and axial skeleton

This study examines functional trade-offs and covariation among skeletal regions in carnivorans to understand their ecological adaptations and landscape topology.

Uncovering the mosaic evolution of the carnivoran skeletal system

The paper examines the evolutionary patterns of different skeletal components in carnivorans, finding that only certain regions show ecological adaptation while others reflect phylogenetic shifts.

A switch in jaw form-function coupling during the evolution of mammals

This paper shows that crown mammals have diverse jaw shapes but stereotyped jaw stiffness, which is genetically based and allows resistance to deformation despite dietary diversity.

Endogenous Rab38 regulates LRRK2's membrane recruitment and substrate Rab phosphorylation in melanocytes

This study identifies Rab38 as a physiological regulator of LRRK2 function in melanocytes, showing it enhances LRRK2 membrane recruitment and substrate phosphorylation.

DCIS genomic signatures define biology and clinical outcome: Human Tumor Atlas Network (HTAN) analysis of TBCRC 038 and RAHBT cohorts

The paper develops a classifier for DCIS recurrence using genomic data from two cohorts and identifies pathways and stroma-specific signatures associated with progression to invasive cancer.