Author

S. H. Strand

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cancer Biology· 4

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Organism:human· 4 Research Focus:differential expression· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:gene regulatory network inference· 2 Approach:machine learning (classical)· 2 Research Focus:clustering· 1

Frequent Co-Authors

C. Zhu· 3 shared E. S. Hwang· 3 shared G. A. Colditz· 3 shared J. R. Marks· 3 shared R. B. West· 3 shared S. Varma· 3 shared S. Vennam· 3 shared A. DeMichele· 2 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

C. Zhu

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4 papers

Recent·Most cited

Single Cell Expression Analysis of Ductal Carcinoma in Situ Identifies Alterations in Epithelial Integrity

X. Qin, S. H. Strand, M. R. Lee, D. G. P. van Ijzendoorn, C. Zhu, S. Vennam, S. Varma, A. Hall, L. King, L. Simpson, X. Luo, G. A. Colditz, S. Jiang, E. S. Hwang, J. R. Marks, , R. B. West

This study uses scRNA-seq to analyze DCIS and normal breast tissue, identifying clonal heterogeneity and cell state changes associated with progression to invasive cancer.

bioRxiv · Oct 10, 2023Cancer Biology

Analysis of ductal carcinoma in situ by self-reported race reveals molecular differences related to outcome.

S. H. Strand, K. E. Houlahan, V. Branch, T. Lynch, B. Harmon, F. Couch, K. Gallagher, M. Kilgore, S. Wei, A. DeMichele, T. King, P. McAuliffe, C. Curtis, K. Owzar, J. R. Marks, , R. B. West

The paper analyzes molecular differences in ductal carcinoma in situ (DCIS) by self-reported race and outcome groups, identifying variations in gene expression, tumor microenvironment, and copy number variations between Black and White women.

bioRxiv · Sep 28, 2023Cancer Biology

DCIS genomic signatures define biology and clinical outcome: Human Tumor Atlas Network (HTAN) analysis of TBCRC 038 and RAHBT cohorts

S. H. Strand, B. Rivero-Gutierrez, K. E. Houlahan, J. A. Seoane, L. M. King, T. Risom, L. A. Simpson, S. Vennam, A. Khan, L. Cisneros, T. Hardman, B. Harmon, F. Couch, K. Gallagher, M. Kilgore, , K Owzar

The paper develops a classifier for DCIS recurrence using genomic data from two cohorts and identifies pathways and stroma-specific signatures associated with progression to invasive cancer.

bioRxiv · Jun 16, 2021 · PreprintCancer Biology

Transition to invasive breast cancer is associated with progressive changes in the structure and composition of tumor stroma

T. Risom, D. R. Glass, C. C. Liu, B. Rivero-Gutierrez, A. Baranski, E. F. McCaffrey, N. F. Greenwald, A. C. Kagel, S. H. Strand, S. Varma, A. Kong, L. Keren, S. Srivastava, C. Zhu, Z. Khair, , M. Angelo

The paper analyzes tumor microenvironment changes from normal to invasive breast cancer using imaging and machine learning, finding coordinated shifts in stromal cell location and function.

bioRxiv · Jan 5, 2021Cancer Biology