Author

J. Ursic-Bedoya

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Physiology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:mouse· 5 Research Focus:host-pathogen & immune response· 4 Research Focus:cancer & tumor microenvironment· 2 Assay:bulk RNA-seq· 1 Organism:human· 1 Organism:rat· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

D. Gregoire· 4 shared C. Chavey· 3 shared U. Hibner· 3 shared E. Assenat· 2 shared G. Desandre· 2 shared T. Tordjmann· 2 shared A. ABDELRAFEE· 1 shared A. Camasses· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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4 shared papersCancer Biology

D. Gregoire

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

FGF19 and its analog Aldafermin cooperate with MYC to induce aggressive hepatocarcinogenesis

J. Ursic-Bedoya, G. Desandre, C. Chavey, P. Marie, A. Polizzi, B. Riviere, H. Guillou, E. Assenat, U. Hibner, D. Gregoire

This study shows that FGF19 and its analog Aldafermin cooperate with MYC to drive aggressive hepatocarcinogenesis in mice, raising concerns about the safety of Aldafermin in patients with compromised livers.

bioRxiv · Sep 15, 2023Cancer Biology

Unraveling human, rodent and snake Kolmioviridae replication to anticipate cross-species transmission

K. Majzoub, P. Khalfi, Z. Denis, G. Merolla, C. Chavey, J. Ursic-Bedoya, L. Soppa, L. Szirovicza, U. Hetzel, J. Dufourt, C. Leyrat, N. Goldmann, K. Goto, E. Verrier, T. F. Baumert, , J. Hepojoki

This study compares the replication of three Kolmioviridae viruses in vitro and in vivo, revealing differences in host range and replication efficiency.

bioRxiv · May 17, 2023 · PreprintMicrobiology

The hormone Fibroblast Growth Factor 19 stimulates water intake

J. Ursic-Bedoya, C. Chavey, L. Meunier, G. Desandre, A.-M. Dupuy, I. Gonzalez-Dopeso Reyes, T. Tordjmann, E. Assenat, U. Hibner, D. Gregoire

This study identifies FGF19 as a stimulator of water intake in mice, with implications for its role in cancer and metabolic disorders.

bioRxiv · Oct 26, 2021 · PreprintPhysiology

Bile Acid pool composition and Gallbladder function are controlled by TGR5 to protect the liver against Bile Acid overload

V. BIDAULT-JOURDAINNE, G. MERLEN, M. GLENISSON, I. DOIGNON, I. GARCIN, N. PEAN, R. BOISGARD, J. URSIC-BEDOYA, M. SERINO, C. ULLMER, L. HUMBERT, A. ABDELRAFEE, E. VIBERT, J.-C. DUCLOS-VALLEE, D. RAINTEAU, T. TORDJMANN

This study shows that TGR5 regulates bile acid pool composition and gallbladder function to protect the liver from bile acid overload in mice and humans.

bioRxiv · Feb 18, 2020 · PreprintPhysiology

CDK8 and CDK19 kinases have non-redundant oncogenic functions in hepatocellular carcinoma

K. Bacevic, S. Prieto, S. Caruso, A. Camasses, G. Dubra, J. Ursic-Bedoya, A. Lozano, J. Butterworth, J. Zucman-rossi, U. Hibner, D. Fisher, D. Gregoire

The paper investigates the roles of CDK8 and CDK19 in hepatocellular carcinoma, finding they are overexpressed and have non-redundant oncogenic functions that interact with TP53.

bioRxiv · Oct 1, 2019 · PreprintCancer Biology