Author

J. Vappiani

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Assay:proteomics· 2 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:imaging· 1

Frequent Co-Authors

D. C. Sevin· 2 shared D. Poeckel· 2 shared G. Bergamini· 2 shared A. Halavatyi· 1 shared A. J. Fisher· 1 shared A. Rutkowska· 1 shared B. Heller· 1 shared C. B. nanthakumar· 1 shared

Activity by Year

2018-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersPhysiology

D. C. Sevin

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Author profile →

2 papers

Recent·Most cited

Multiomic and quantitative label-free microscopy-based analysis of ex vivo culture and TGFbeta1 stimulation of human precision-cut lung slices

M. M. Khan, D. Poeckel, A. Halavatyi, F. Stein, J. Vappiani, D. C. Sevin, C. Tischer, N. Zinn, J. D. Eley, N. S. Gudmann, T. Muley, H. Winter, A. J. Fisher, C. B. nanthakumar, G. Bergamini, R. Pepperkok

The paper uses multiomic and microscopy techniques to study fibrosis in human lung slices, showing increased collagen deposition with TGFbeta1 stimulation and a novel SHG-based method to quantify it.

bioRxiv · Dec 13, 2019Physiology

Proteome thermal stability reflects organ physiology and identifies drug-target engagement in vivo

J. Perrin, T. Werner, N. Kurzawa, D. D. Childs, M. Kalxdorf, A. Rutkowska, D. Poeckel, D. C. Sevin, E. Stonehouse, K. Strohmer, B. Heller, D. Thomson, J. Vappiani, J. Krause, H. C. Eberl, , G. Bergamini

This study introduces tissue-TPP and blood-CETSA to measure proteome thermal stability, revealing organ physiology and drug-target engagement in vivo.

bioRxiv · Dec 20, 2018 · PreprintCell Biology