Author

J. W. Hwang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Organism:human· 1 Organism:mouse· 1 Assay:organoid / primary culture· 1

Frequent Co-Authors

A. Bennaceur Griscelli· 1 shared A. Foudi· 1 shared A. G. Turhan· 1 shared B. Liu· 1 shared C. Desterke· 1 shared F. Griscelli· 1 shared I. R. Correa· 1 shared J. J. Patard· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

A. Bennaceur Griscelli

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2 papers

Recent·Most cited

GSK-3484862 targets DNMT1 for degradation in cells

Q. Chen, Y. Zeng, J. W. Hwang, B. Liu, N. Dai, I. R. Correa, M. R. Estecio, X. Zhang, M. A. Santos, T. Chen, X. Cheng

This paper shows that GSK-3484862 targets DNMT1 for degradation in cancer cells and mouse embryonic stem cells, leading to DNA hypomethylation without reducing DNMT1 mRNA levels.

NAR Cancer · May 17, 2023Peer-reviewedCancer Biology

iPSC-derived Cancer Organoids Recapitulate Genomic and Phenotypic Alterations of c-met-mutated Hereditary Kidney Cancer

J. W. Hwang, C. Desterke, O. Feraud, S. Richard, S. Ferlicot, V. Verkarre, J. J. Patard, J. Loisel-Duwattez, A. Foudi, F. Griscelli, A. Bennaceur Griscelli, A. G. Turhan

The paper generates c-met-mutated iPSC-derived kidney organoids that recapitulate genomic and phenotypic features of PRCC, identifying common genes and validating their expression in both organoids and patient tumors.

bioRxiv · Jan 11, 2019 · PreprintCancer Biology