Author

M. A. Santos

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 3 Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 4 Organism:Drosophila· 3 Research Focus:development & morphogenesis· 2 Organism:mouse· 2 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1

Frequent Co-Authors

M. Matos· 3 shared M. Santos· 3 shared P. Simoes· 3 shared A. Carromeu-Santos· 2 shared A. S. Quina· 2 shared A. Adam· 1 shared A. J. Auguste· 1 shared B. Liu· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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3 shared papersEvolutionary Biology

M. Matos

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

GSK-3484862 targets DNMT1 for degradation in cells

Q. Chen, Y. Zeng, J. W. Hwang, B. Liu, N. Dai, I. R. Correa, M. R. Estecio, X. Zhang, M. A. Santos, T. Chen, X. Cheng

This paper shows that GSK-3484862 targets DNMT1 for degradation in cancer cells and mouse embryonic stem cells, leading to DNA hypomethylation without reducing DNMT1 mRNA levels.

NAR Cancer · May 17, 2023Peer-reviewedCancer Biology

Humoral and T-cell-mediated responses to a pre-clinical Zika vaccine candidate that utilizes a unique insect-specific flavivirus platform

D. L. Porier, A. Adam, L. Kang, P. Michalak, J. Tupik, M. A. Santos, C. Lee, I. C. Allen, T. Wang, A. J. Auguste

This study evaluates immune responses to an ISFV-based Zika vaccine, showing neutralizing antibodies and T-cells contribute to protection.

bioRxiv · Mar 1, 2023 · PreprintMicrobiology

No evidence for short-term evolutionary response to a warming environment in Drosophila

M. A. Santos, A. Carromeu-Santos, A. S. Quina, M. Santos, M. Matos, P. Simoes

This study shows no significant evolutionary adaptation to warming in Drosophila after nine generations, with historical background and trait-specific effects influencing thermal responses.

bioRxiv · Feb 19, 2021Evolutionary Biology

High developmental temperature leads to low reproduction despite adult temperature

M. A. Santos, A. Carromeu-Santos, A. S. Quina, M. Santos, M. Matos, P. Simoes

This study examines how developmental temperature affects reproductive performance in Drosophila subobscura, finding that high developmental temperatures reduce reproduction regardless of adult temperature.

bioRxiv · Jun 8, 2020Evolutionary Biology

How phenotypic convergence arises in experimental evolution

P. Simoes, I. Fragata, J. Santos, M. A. Santos, M. Santos, M. R. Rose, M. Matos

This study examines whether initially differentiated Drosophila subobscura populations converge to similar adaptive states after 60 generations in a common environment, finding persistent differentiation despite convergence patterns.

bioRxiv · Jun 11, 2019Evolutionary Biology