J. W. Kappler

Immune-based mutation classification enables neoantigen prioritization and immune feature discovery in cancer immunotherapy

The paper classifies neoantigens based on immune interactions and improves their prioritization for cancer immunotherapy.

Tolerance induction in memory CD4 T cells is partial and reversible

This study shows that memory CD4 T cells can partially tolerate antigen re-exposure but can be reversed by adjuvant-containing reactivation.