Author

J. I. Gray

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Assay:CITE-seq· 1

Frequent Co-Authors

M. K. MacLeod· 2 shared P. Garside· 2 shared S. Al Khabouri· 2 shared T. D. Otto· 2 shared A. Masdefiol Garriga· 1 shared C. Pirillo· 1 shared C. T. Prendergast· 1 shared E. Brennan· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersImmunology

M. K. MacLeod

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Lung influenza virus specific memory CD4 T cell location and optimal cytokine production are dependent on interactions with lung antigen-presenting cells

K. E. Hargrave, J. C. Worrell, C. Pirillo, E. Brennan, A. Masdefiol Garriga, J. I. Gray, T. Purnell, E. W. Roberts, M. K. MacLeod

bioRxiv · Sep 19, 2023Immunology

TCRβ Sequencing Reveals Spatial and Temporal Evolution of Clonal CD4 T cell Responses in a Breach of Tolerance Model of Inflammatory Arthritis

S. Al Khabouri, R. A. Benson, C. T. Prendergast, J. I. Gray, T. D. Otto, J. M. Brewer, P. Garside

The paper uses TCRβ sequencing to track CD4 T cell clonality and diversity in a mouse model of inflammatory arthritis, finding increased clonality and diversity in lymph nodes over time, with implications for tolerogenic therapy timing.

bioRxiv · Nov 15, 2020Immunology

Tolerance induction in memory CD4 T cells is partial and reversible

J. I. Gray, S. Al Khabouri, F. Morton, E. Clambey, L. Gapin, J. L. Matsuda, J. W. Kappler, P. Marrack, P. Garside, T. D. Otto, M. K. MacLeod

This study shows that memory CD4 T cells can partially tolerate antigen re-exposure but can be reversed by adjuvant-containing reactivation.

bioRxiv · May 25, 2020Immunology