Tolerance induction in memory CD4 T cells is partial and reversible
J. I. Gray, S. Al Khabouri, F. Morton, E. Clambey, L. Gapin, J. L. Matsuda, J. W. Kappler, P. Marrack, P. Garside, T. D. Otto, M. K. MacLeod
This study shows that memory CD4 T cells can partially tolerate antigen re-exposure but can be reversed by adjuvant-containing reactivation.
bioRxiv · May 25, 2020Immunology