J. W. Millington

The paper identifies transformer as a key gene regulating sex differences in fat storage in Drosophila by modulating the adipokinetic hormone pathway in neurons.

This study shows that a low sugar diet increases body size in both male and female Drosophila larvae, but affects their insulin/TOR signaling and metabolism differently.

This study shows that altering insulin/insulin-like growth factor signaling (IIS) activity in Drosophila larvae has sex-biased effects on body size, with inhibition reducing female size more than males and augmentation increasing male size more than females.

The paper identifies a female-specific increase in insulin pathway activity as the mechanism behind sex differences in nutrient-dependent body size plasticity in Drosophila.