Author

L. W. Wat

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 3 Biochemistry· 2

Signature Assays, Organisms & Methods

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Organism:Drosophila· 3 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Research Focus:development & morphogenesis· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Approach:genetic perturbation / CRISPR· 2 Approach:deep learning· 1

Frequent Co-Authors

E. J. Rideout· 3 shared J. W. Millington· 3 shared G. P. Brownrigg· 2 shared K. J. Svensson· 2 shared M. Zhao· 2 shared P. J. Basner-Collins· 2 shared Z. Sun· 2 shared A. L. Markhard· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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3 shared papersPhysiology

E. J. Rideout

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

A PTER-dependent pathway of taurine metabolism linked to energy balance

W. Wei, X. Lyu, A. L. Markhard, S. Fu, R. E. Mardjuki, P. E. Cavanagh, X. Zeng, J. Rajniak, N. Lu, S. Xiao, M. Zhao, M. Dolores Moya-Garzon, S. D. Truong, C. J. Chou, L. W. Wat, , J. Z. Long

This study identifies PTER as the taurine N-acetyltransferase/hydrolase, showing its role in regulating N-acetyltaurine levels and linking it to energy balance and metabolic phenotypes.

bioRxiv · Mar 21, 2024 · PreprintBiochemistry

AlphaFold2 enables accurate deorphanization of ligands to single-pass receptors

N. Banhos Danneskiold-Samsoee, D. Kavi, K. M. Jude, S. B. Nissen, L. W. Wat, L. Coassolo, M. Zhao, G. Asae Santana-Oikawa, B. B. Broido, K. C. Garcia, K. J. Svensson

The paper uses AlphaFold2 to predict ligand-receptor interactions for single-pass transmembrane receptors with high accuracy.

bioRxiv · Mar 16, 2023Biochemistry

Sex determination gene transformer regulates the male-female difference in Drosophila fat storage via the adipokinetic hormone pathway

L. W. Wat, Z. S. Chowdhury, J. W. Millington, P. Biswas, E. J. Rideout

The paper identifies transformer as a key gene regulating sex differences in fat storage in Drosophila by modulating the adipokinetic hormone pathway in neurons.

eLife · Oct 21, 2021Peer-reviewedPhysiology

A low sugar diet enhances Drosophila body size in males and females via sex-specific mechanisms

J. W. Millington, L. W. Wat, Z. Sun, P. J. Basner-Collins, G. P. Brownrigg, E. J. Rideout

This study shows that a low sugar diet increases body size in both male and female Drosophila larvae, but affects their insulin/TOR signaling and metabolism differently.

bioRxiv · Mar 3, 2021 · PreprintPhysiology

Female-specific upregulation of insulin pathway activity mediates the sex difference in Drosophila body size plasticity

J. W. Millington, C. Chao, Z. Sun, P. J. Basner-Collins, G. P. Brownrigg, L. W. Wat, B. Hudry, I. Miguel-Aliaga, E. J. Rideout

The paper identifies a female-specific increase in insulin pathway activity as the mechanism behind sex differences in nutrient-dependent body size plasticity in Drosophila.

bioRxiv · Apr 22, 2020Physiology