E. J. Rideout

Auxin Exposure Disrupts Feeding Behavior and Fatty Acid Metabolism in Adult Drosophila

This study shows auxin exposure affects adult Drosophila feeding behavior and fatty acid metabolism but not fecundity or progeny survival.

Consideration of sex as a biological variable in diabetes research across twenty years

This study assesses the inclusion of biological sex in diabetes research over 20 years, finding less than 15% of papers used sex-based analysis and highlighting the need for improved consideration of sex as a variable.

Sex differences in islet stress responses support female beta cell resilience

This study identifies sex differences in beta cell stress responses, showing female beta cells are more resilient to ER stress in both human and mouse models.

Sex determination gene transformer regulates the male-female difference in Drosophila fat storage via the adipokinetic hormone pathway

The paper identifies transformer as a key gene regulating sex differences in fat storage in Drosophila by modulating the adipokinetic hormone pathway in neurons.

A low sugar diet enhances Drosophila body size in males and females via sex-specific mechanisms

This study shows that a low sugar diet increases body size in both male and female Drosophila larvae, but affects their insulin/TOR signaling and metabolism differently.

Beta-cell specific Insr deletion promotes insulin hypersecretion and improves glucose tolerance prior to global insulin resistance

This study shows that deleting the insulin receptor in beta-cells improves glucose tolerance in some mice but not others, depending on age and diet.

Female-specific upregulation of insulin pathway activity mediates the sex difference in Drosophila body size plasticity

The paper identifies a female-specific increase in insulin pathway activity as the mechanism behind sex differences in nutrient-dependent body size plasticity in Drosophila.